Drug Designing and Biomarkers

 Drug design is an inventive process to find new medication centered on the knowledge of the biological target. It is also known as also known as rational drug design. A drug is most a small molecule that inhibits or activates the function of a biomolecule, which in results into a therapeutic benefit to the patient. Drug design commonly relies on computational techniques. This type of modeling is often mentioned to as computer-aided drug design. Drug design that depends on the knowledge of the 3D structure of the target is known as structure-based drug design. The main methods available for drug design are structure-based drug design and ligand-based drug design. The structure-based drug designing also known as direct drug design involves the three-dimensional structure of a drug target interacting with small molecules is used to guide drug discovery. 

Biomarkers are biological measures of a biological state. It is a characteristic that is accurately measured and evaluated as an indicator of natural biological processes, pathogenic processes or pharmacological responses to a therapeutic intervention.

 

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